Ep. 7: Carbs vs. Fats and General Macronutrient Guidelines — Key Takeaways
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Ep. 7: Carbs vs. Fats and General Macronutrient Guidelines
Jay Feldman Wellness1h 9mMay 11, 2020
Watch the originalEat a baseline of 0.6–0.8g protein per pound of bodyweight, at least 150g carbohydrates daily, and 20–30g of saturated/monounsaturated fat per meal to support hormones, metabolism, and stable energy without triggering stress pathways.
Key takeaways
Fat oxidation produces ~30% less CO2 than carb oxidation, reducing oxygenation and vasodilation
Fat oxidation produces ~30% less CO2 than carb oxidation, reducing oxygenation and vasodilation
- Less CO2 at the cell reduces oxygen offloading from hemoglobin (Bohr effect) and removes CO2's protective role against reactive oxygen and nitrogen species.
- CO2 is the primary physiological vasodilator; nitric oxide (the mainstream alternative) vasodilates by binding cytochrome c oxidase — shutting down the electron transport chain.
Minimum 150g carbs/day prevents stress hormone cascade even at rest
Minimum 150g carbs/day prevents stress hormone cascade even at rest
- Below 150g, body uses gluconeogenesis via cortisol to produce glucose — triggering downstream suppression of thyroid and reproductive hormones.
- Glucagon elevation (a stress hormone) is the key feature of diabetes and rises whenever cellular energy is low.
Low free fatty acids activate the HPA axis and trigger adrenaline release — same as low blood sugar
Low free fatty acids activate the HPA axis and trigger adrenaline release — same as low blood sugar
- Research shows when free fatty acids drop too low, catecholamine release follows; administering exogenous free fatty acids stops this response.
- This parallels the glucagon/adrenaline/cortisol cascade from low glucose, establishing fat as an equally required nutrient with its own stress pathway.
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In this video
- 1mintro
- 2mcarbs vs. fats (introduction and effects on hormones)
- 15mcarbs vs fats (energetic effects)
- 25mCO2 is not a waste product; the importance of CO2 for energy balance
- 33mthe roles for both carb and fat oxidation; the Randle Cycle and fuel partitioning
- 46mother reasons why we need carbs and fats (hormones, digestion, structure)
- 55mprotein functions
- 57mgeneral macronutrient guidelines
“elevated glucagon is basically the key feature of diabetes and is increased when we have low energy, essentially, low cellular energy.”
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