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You've Been Lied to About Sugar & Alzheimer's — Key Takeaways

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You've Been Lied to About Sugar & Alzheimer's

Jay Feldman Wellness20mOct 20, 2026

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A single blood sugar spike after eating grapes on a ketogenic diet reflects temporary physiological insulin resistance, not fruit being harmful — slowly reintroducing whole fruits over weeks will normalize the response.

Key takeaways

Low-carb dieters: reintroduce fruit gradually over days, not all at once

Low-carb dieters: reintroduce fruit gradually over days, not all at once

  • Physiological insulin resistance from low-carb causes temporary glucose spikes; resolves after days of carb intake
  • Gut microbiome needs slow adaptation to fermentable carbs to avoid bloating/gas

CGM glucose spikes mislead low-carb dieters into avoiding healthy carbs

CGM glucose spikes mislead low-carb dieters into avoiding healthy carbs

  • Normal physiological insulin resistance after ketogenic diets causes elevated post-meal glucose readings
  • This temporary adaptive response is not pathological or evidence of harm

Alzheimer's pathology linked to low brain glucose use, not high blood sugar

Alzheimer's pathology linked to low brain glucose use, not high blood sugar

  • Reduced glucose uptake and metabolism in the brain correlates with more tau and amyloid-beta accumulation
  • Brain hypometabolism is a fundamental feature of Alzheimer's disease

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In this video

  1. 1mDr Boz parrots Robert Lustig: they’re both wrong about fructose
  2. 3mconcerns with blood sugar spikes when reintroducing carbs and whether using a CGM is worth it
  3. 4mless, not more, glucose uptake in the brain creates the conditions for Alzheimer’s disease
  4. 8mpoor glucose utilization as a driver of Alzheimer’s and dementia
  5. 10mreducing carbohydrate intake causes insulin resistance and less metabolic flexibility
  6. 14mpossible reasons for Dr Boz’s high blood sugar and our advice for Dr Boz

“The fundamental defects are energetic defects inside the neurons where the cells cannot use glucose effectively.”

— Mike (translated)

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